BDBM50050788 2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-bis-(3-methoxy-phenyl)-propionic acid::CHEMBL303390

SMILES COc1cccc(c1)C(OC)(C(Oc1nc(OC)cc(OC)n1)C(O)=O)c1cccc(OC)c1

InChI Key InChIKey=NKUABLQDYCDPIT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050788   

TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050788(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-...)
Affinity DataKi:  22nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050788(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-...)
Affinity DataKi:  1.30E+3nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed