BDBM50052027 (E)-3-[6-(2,6-Dichloro-phenylsulfanylmethyl)-3-phenethyloxy-pyridin-2-yl]-acrylic acid::CHEMBL90214::SB-209247::Ticolubant
SMILES OC(=O)\C=C\c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccccc1
InChI Key InChIKey=ZJLFOOWTDISDIO-ZRDIBKRKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50052027
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 0.780nMAssay Description:Inhibition of [3H]-LTB4 binding to human neutrophilsMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Compound was tested for binding affinity against human neutrophil LTB4 (leukotriene) receptorMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.68E+4nMAssay Description:Inhibitory concentration LTB4 with [3H]-LTD4 in LTD4 receptor binding assayMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 8.20E+3nMAssay Description:Concentration required to inhibit RBL-1 supernatant 5-lipoxygenaseMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.25E+3nMAssay Description:Inhibitory concentration against LTB4 with [3H]- fMLP in receptor binding assayMore data for this Ligand-Target Pair