BDBM50056562 1-(2-Benzhydryloxy-ethyl)-4-(3-furan-2-yl-propyl)-piperazine::CHEMBL163273

SMILES C(CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)Cc1ccco1

InChI Key InChIKey=DJVBTASHFYCXHN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50056562   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50056562(1-(2-Benzhydryloxy-ethyl)-4-(3-furan-2-yl-propyl)-...)
Affinity DataIC50:  8.5nMAssay Description:Reuptake inhibition at the dopamine transporter labeled with radioligand [3H]-dopamine on synaptosomes obtained from rat caudate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50056562(1-(2-Benzhydryloxy-ethyl)-4-(3-furan-2-yl-propyl)-...)
Affinity DataIC50:  1.52E+3nMAssay Description:Binding affinity at the serotonin transporter using [125I]-RTI-55 in rat caudate membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50056562(1-(2-Benzhydryloxy-ethyl)-4-(3-furan-2-yl-propyl)-...)
Affinity DataIC50:  6.5nMAssay Description:Binding affinity at the dopamine transporter using [125I]-RTI-55 in rat caudate membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50056562(1-(2-Benzhydryloxy-ethyl)-4-(3-furan-2-yl-propyl)-...)
Affinity DataIC50:  2.55E+3nMAssay Description:Reuptake inhibition at the dopamine transporter labeled with radioligand [3H]-5-HT on synaptosomes obtained from whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed