BDBM50056684 CHEMBL3341941::US10688093, Compound 382_0087_7249::US11701353, Compound 382_0087_7249

SMILES COc1cc(cc(OC)c1OC)-c1cc(cnc1N)-c1ccc(O)cc1

InChI Key InChIKey=PCGVHKSBFKSOEH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50056684   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056684(CHEMBL3341941 | US10688093, Compound 382_0087_7249...)
Affinity DataIC50:  580nMAssay Description:Inhibition of TGFbeta1-induced TGFbeta type 1 ALK5 in HEK293T cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Pathways Neuro Pharma

US Patent
LigandPNGBDBM50056684(CHEMBL3341941 | US10688093, Compound 382_0087_7249...)
Affinity DataIC50:  1.73E+3nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetActivin receptor type-1(Mus musculus)
Massachusetts Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50056684(CHEMBL3341941 | US10688093, Compound 382_0087_7249...)
Affinity DataIC50:  20nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed