BDBM50057581 4-(4-Fluoro-5-phenyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide::CHEMBL29766
SMILES NS(=O)(=O)c1ccc(cc1)-n1nc(c(F)c1-c1ccccc1)C(F)(F)F
InChI Key InChIKey=FUHLJNQTSZQWBE-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50057581
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 830nMAssay Description:In vitro inhibitory concentration required to block recombinant human prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Inhibition of COX1 (unknown origin)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development
Curated by ChEMBL
Searle Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2 at 25 degrees.More data for this Ligand-Target Pair