BDBM50057922 2-(3-Fluoro-5-methyl-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole::CHEMBL42884

SMILES Cc1cc(F)cc(c1)-c1nc(cn1-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F

InChI Key InChIKey=MEAMLMDMYOLDGW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50057922   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50057922(2-(3-Fluoro-5-methyl-phenyl)-1-(4-methanesulfonyl-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required to inhibit human prostaglandin G/H synthase 1 (COX-1) by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
University Of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50057922(2-(3-Fluoro-5-methyl-phenyl)-1-(4-methanesulfonyl-...)
Affinity DataIC50:  1.09E+8nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50057922(2-(3-Fluoro-5-methyl-phenyl)-1-(4-methanesulfonyl-...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50057922(2-(3-Fluoro-5-methyl-phenyl)-1-(4-methanesulfonyl-...)
Affinity DataIC50:  110nMAssay Description:Concentration required to inhibit human Prostaglandin G/H synthase 2 (COX-2) by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed