BDBM50058758 CHEMBL3335422

SMILES OC1(CCCCC1)C#Cc1ccc(NC(=O)c2ccc(CN3CCN(Cc4cccnc4)CC3)cc2)cc1

InChI Key InChIKey=FCBHWWXOEQMAMX-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50058758   

TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Eisai

Curated by ChEMBL

LigandBDBM50058758(CHEMBL3335422)Copy SMILESCopy InChI

Affinity DataIC50: >200nMAssay Description:Inhibition of HIF1 signaling in human U251 cells expressing VEGF by VEGF promoter-driven PLAP reporter gene assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI