BDBM50058761 CHEMBL3335420
SMILES O=C(Nc1ccc(cc1)C#Cc1cccnc1)c1ccc(CN2CCN(Cc3cccnc3)CC2)cc1
InChI Key InChIKey=AXIGJAOOOZKTOP-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50058761
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Eisai
Curated by ChEMBL
Eisai
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of HIF1 signaling in human U251 cells expressing VEGF by VEGF promoter-driven PLAP reporter gene assayMore data for this Ligand-Target Pair