BDBM50058762 CHEMBL3335419

SMILES O=C(Nc1ccc(cc1)C#Cc1ccccc1)c1ccc(CN2CCN(Cc3cccnc3)CC2)cc1

InChI Key InChIKey=MUTIAFGLMQDVIR-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50058762   

TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Eisai

Curated by ChEMBL

LigandBDBM50058762(CHEMBL3335419)Copy SMILESCopy InChI

Affinity DataIC50:  7.90nMAssay Description:Inhibition of HIF1 signaling in human U251 cells expressing VEGF by VEGF promoter-driven PLAP reporter gene assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI