BDBM50058769 CHEMBL3335412

SMILES FC(F)(F)c1ccc(NC(=O)c2ccc(CC3CCN(Cc4ccncc4)CC3)cc2)cc1

InChI Key InChIKey=ZSQSPMPLTBBXJV-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50058769   

TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Eisai

Curated by ChEMBL

LigandBDBM50058769(CHEMBL3335412)Copy SMILESCopy InChI

Affinity DataIC50:  110nMAssay Description:Inhibition of HIF1 signaling in human U251 cells expressing VEGF by VEGF promoter-driven PLAP reporter gene assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI