BDBM50058776 CHEMBL3335405

SMILES FC(F)(F)c1ccc(NC(=O)c2ccc(CN3CCOCC3)s2)cc1

InChI Key InChIKey=HZWQBWRQZUCRHI-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50058776   

TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Eisai

Curated by ChEMBL

LigandBDBM50058776(CHEMBL3335405)Copy SMILESCopy InChI

Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of HIF1 signaling in human U251 cells expressing VEGF by VEGF promoter-driven PLAP reporter gene assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI