BDBM50058832 CHEMBL3325875

SMILES CC(=O)N1CCN(CC1)c1c(\C=N\Nc2nc3ccccc3nc2O)c(C)nn1-c1ccccc1

InChI Key InChIKey=GFECJSAJCVJBKE-WGOQTCKBSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50058832   

TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Dokki

Curated by ChEMBL
LigandPNGBDBM50058832(CHEMBL3325875)
Affinity DataIC50:  460nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGH2 production using arachidonic acid substrate by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Central South University

Curated by ChEMBL
LigandPNGBDBM50058832(CHEMBL3325875)
Affinity DataIC50:  460nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Central South University

Curated by ChEMBL
LigandPNGBDBM50058832(CHEMBL3325875)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of COX-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dokki

Curated by ChEMBL
LigandPNGBDBM50058832(CHEMBL3325875)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGH2 production using arachidonic acid substrate by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed