BDBM50060966 4-Phenoxy-benzoic acid::CHEMBL107518::US10322118, Entry 11

SMILES OC(=O)c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=RYAQFHLUEMJOMF-UHFFFAOYSA-N

Data  2 IC50  2 Kd

PDB links: 3 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50060966   

TargetRegulatory protein E2(Human papillomavirus type 16)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060966(4-Phenoxy-benzoic acid | CHEMBL107518 | US10322118...)
Affinity DataKd:  9.10E+6nMAssay Description:Dissociation constant after binding to human papillomavirus E2 DNA-binding domain (DBD) by observing the changes in [15N]-HSQC spectra.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPutative hydrolase(Pseudomonas aeruginosa (strain UCBPP-PA14))
Dartmouth College

US Patent
LigandPNGBDBM50060966(4-Phenoxy-benzoic acid | CHEMBL107518 | US10322118...)
Affinity DataIC50: >1.00E+5nMAssay Description:The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-lactamase(Klebsiella pneumoniae)
Uit The Arctic University Of Norway

Curated by ChEMBL
LigandPNGBDBM50060966(4-Phenoxy-benzoic acid | CHEMBL107518 | US10322118...)
Affinity DataIC50:  8.70E+5nMAssay Description:Inhibition of native signal containing Klebsiella pneumoniae OXA-48 using nitrocefin substrate pre-incubated for 5 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Klebsiella pneumoniae)
Uit The Arctic University Of Norway

Curated by ChEMBL
LigandPNGBDBM50060966(4-Phenoxy-benzoic acid | CHEMBL107518 | US10322118...)
Affinity DataKd:  6.60E+5nMAssay Description:Binding affinity to native signal deficient and TEV cleavage site containing His-tagged Klebsiella pneumoniae OXA-48 expressed in Escherichia coli as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed