BDBM50061296 1-[4-(2,3-Dimethoxy-phenyl)-piperazin-1-yl]-2-[8-(4-methyl-piperazin-1-yl)-naphthalen-2-yloxy]-ethanone::CHEMBL338015

SMILES COc1cccc(N2CCN(CC2)C(=O)COc2ccc3cccc(N4CCN(C)CC4)c3c2)c1OC

InChI Key InChIKey=JHJZWCFGCZBIET-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50061296   

Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50061296(1-[4-(2,3-Dimethoxy-phenyl)-piperazin-1-yl]-2-[8-(...)
Affinity DataKi:  0.440nMAssay Description:Receptor binding affinity for cloned human 5-hydroxytryptamine 1B receptor in Cos-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50061296(1-[4-(2,3-Dimethoxy-phenyl)-piperazin-1-yl]-2-[8-(...)
Affinity DataKi:  0.620nMAssay Description:Receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptor in Cos-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50061296(1-[4-(2,3-Dimethoxy-phenyl)-piperazin-1-yl]-2-[8-(...)
Affinity DataKi:  13.4nMAssay Description:Receptor binding affinity for cloned human 5-hydroxytryptamine 1A receptor in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50061296(1-[4-(2,3-Dimethoxy-phenyl)-piperazin-1-yl]-2-[8-(...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at 5-hydroxytryptamine 1B receptor by measuring the inhibition of forskolin-stimulated cAMP formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed