BDBM50061467 1-[4-(8-Chloro-3-hydroxymethyl-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-ethanone::CHEMBL268695

SMILES [#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccc(Cl)cc2-[#6]-[#6]-c2cc(-[#6]-[#8])cnc-12

InChI Key InChIKey=MEWHFGOCTSSITK-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50061467   

TargetHistamine H1 receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50061467(1-[4-(8-Chloro-3-hydroxymethyl-5,6-dihydro-benzo[5...)
Affinity DataKi:  20nMAssay Description:Ability to displace [3H]-pyrilamine from H1 receptor in rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50061467(1-[4-(8-Chloro-3-hydroxymethyl-5,6-dihydro-benzo[5...)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibitory activity against recombinant human farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed