BDBM50064518 3-{(3R,4R)-1-[(E)-3-(2-Chloro-phenyl)-allyl]-3,4-dimethyl-piperidin-4-yl}-phenol::3-{1-[3-(2-Chloro-phenyl)-allyl]-3,4-dimethyl-piperidin-4-yl}-phenol::CHEMBL50594::RTI-5989-23

SMILES C[C@H]1CN(C\C=C\c2ccccc2Cl)CC[C@@]1(C)c1cccc(O)c1

InChI Key InChIKey=RRGWRLNJBLFYOG-KISUKSLOSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50064518   

TargetMu-type opioid receptor(GUINEA PIG)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50064518(3-{(3R,4R)-1-[(E)-3-(2-Chloro-phenyl)-allyl]-3,4-d...)
Affinity DataKi:  0.0260nMAssay Description:The compound was tested for antagonist activity by selective inhibition of [35S]-GTP-gammaS, binding to Opioid receptor mu 1 in Guinea pig caudate st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50064518(3-{(3R,4R)-1-[(E)-3-(2-Chloro-phenyl)-allyl]-3,4-d...)
Affinity DataKi:  0.567nMAssay Description:The compound was tested for antagonist activity by selective inhibition of [35S]-GTP-gammaS, binding in Guinea pig caudate stimulated by U69,593 to O...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50064518(3-{(3R,4R)-1-[(E)-3-(2-Chloro-phenyl)-allyl]-3,4-d...)
Affinity DataKi:  1.10nMAssay Description:The compound was tested for antagonist activity by selective inhibition of [35S]-GTP-gammaS, binding in Guinea pig caudate stimulated by SMC-80 (Opio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50064518(3-{(3R,4R)-1-[(E)-3-(2-Chloro-phenyl)-allyl]-3,4-d...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of binding of [3H]DAMGO to Opioid receptor mu 1 in guinea pig membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50064518(3-{(3R,4R)-1-[(E)-3-(2-Chloro-phenyl)-allyl]-3,4-d...)
Affinity DataKi:  1.12nMAssay Description:Inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50064518(3-{(3R,4R)-1-[(E)-3-(2-Chloro-phenyl)-allyl]-3,4-d...)
Affinity DataKi:  35.8nMAssay Description:Inhibition of [3H]U69,593 binding to Opioid receptor kappa 1 of guinea pig membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50064518(3-{(3R,4R)-1-[(E)-3-(2-Chloro-phenyl)-allyl]-3,4-d...)
Affinity DataKi:  36nMAssay Description:Inhibition of binding of [3H]U69, 593 to Opioid receptor kappa 1 in guinea pig membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50064518(3-{(3R,4R)-1-[(E)-3-(2-Chloro-phenyl)-allyl]-3,4-d...)
Affinity DataKi:  168nMAssay Description:Inhibition of binding of [3H]DADLE to Opioid receptor delta 1 in guinea pig membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50064518(3-{(3R,4R)-1-[(E)-3-(2-Chloro-phenyl)-allyl]-3,4-d...)
Affinity DataKi:  168nMAssay Description:Inhibition of [3H]-DADLE binding to Opioid receptor delta 1 of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed