BDBM50064518 3-{(3R,4R)-1-[(E)-3-(2-Chloro-phenyl)-allyl]-3,4-dimethyl-piperidin-4-yl}-phenol::3-{1-[3-(2-Chloro-phenyl)-allyl]-3,4-dimethyl-piperidin-4-yl}-phenol::CHEMBL50594::RTI-5989-23
SMILES C[C@H]1CN(C\C=C\c2ccccc2Cl)CC[C@@]1(C)c1cccc(O)c1
InChI Key InChIKey=RRGWRLNJBLFYOG-KISUKSLOSA-N
Data 9 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50064518
Affinity DataKi: 0.0260nMAssay Description:The compound was tested for antagonist activity by selective inhibition of [35S]-GTP-gammaS, binding to Opioid receptor mu 1 in Guinea pig caudate st...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 0.567nMAssay Description:The compound was tested for antagonist activity by selective inhibition of [35S]-GTP-gammaS, binding in Guinea pig caudate stimulated by U69,593 to O...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:The compound was tested for antagonist activity by selective inhibition of [35S]-GTP-gammaS, binding in Guinea pig caudate stimulated by SMC-80 (Opio...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of binding of [3H]DAMGO to Opioid receptor mu 1 in guinea pig membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.12nMAssay Description:Inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 35.8nMAssay Description:Inhibition of [3H]U69,593 binding to Opioid receptor kappa 1 of guinea pig membranesMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 36nMAssay Description:Inhibition of binding of [3H]U69, 593 to Opioid receptor kappa 1 in guinea pig membranesMore data for this Ligand-Target Pair
Affinity DataKi: 168nMAssay Description:Inhibition of binding of [3H]DADLE to Opioid receptor delta 1 in guinea pig membranesMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 168nMAssay Description:Inhibition of [3H]-DADLE binding to Opioid receptor delta 1 of rat brain membranesMore data for this Ligand-Target Pair