BDBM50068356 CHEMBL3402334

SMILES COc1ccc2cc(ccc2c1)C(C)c1nc2s\c(=C/c3ccc(Br)s3)c(=O)n2n1

InChI Key InChIKey=KJAZUGFAZMQIBZ-WQRHYEAKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50068356   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50068356(CHEMBL3402334)
Affinity DataIC50:  1.73E+4nMAssay Description:Inhibition of human recombinant COX-2 using PGH2 as substrate incubated for 10 mins prior to arachidonic acid addition measured after 2 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50068356(CHEMBL3402334)
Affinity DataIC50:  3.98E+4nMAssay Description:Inhibition of ovine recombinant COX-1 using PGH2 as substrate incubated for 10 mins prior to arachidonic acid addition measured after 2 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed