BDBM50069104 CHEMBL1449583::US9182402, 4

SMILES Cc1cccc(c1)C1Nc2cccc3cccc(N1)c23

InChI Key InChIKey=HPFJVSRZYNTHHT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50069104   

TargetSerine protease hepsin(Homo sapiens (Human))
Fred Hutchinson Cancer Research Center

US Patent
LigandPNGBDBM50069104(CHEMBL1449583 | US9182402, 4)
Affinity DataIC50:  350nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine protease hepsin(Homo sapiens (Human))
Fred Hutchinson Cancer Research Center

US Patent
LigandPNGBDBM50069104(CHEMBL1449583 | US9182402, 4)
Affinity DataIC50:  350nMAssay Description:Inhibition of hepsin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Fred Hutchinson Cancer Research Center

US Patent
LigandPNGBDBM50069104(CHEMBL1449583 | US9182402, 4)
Affinity DataIC50: >2.00E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTrypsin(Sus scrofa)
Fred Hutchinson Cancer Research Center

US Patent
LigandPNGBDBM50069104(CHEMBL1449583 | US9182402, 4)
Affinity DataIC50:  1.96E+4nMAssay Description:To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleav...More data for this Ligand-Target Pair
In DepthDetails US Patent