BDBM50072387 4-Chloro-N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-benzenesulfonamide::CHEMBL320228

SMILES O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1

InChI Key InChIKey=LHBPQVTZRYOGPP-NRFANRHFSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072387   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072387(4-Chloro-N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-eth...)
Affinity DataIC50:  1.00E+4nMAssay Description:Beta-2 adrenergic receptor binding affinity in CHO cells expressing cloned human receptor in the presence of 125 I-iodocyanopindololMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072387(4-Chloro-N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-eth...)
Affinity DataEC50:  49nMAssay Description:Agonism against Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072387(4-Chloro-N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-eth...)
Affinity DataIC50:  3.00E+4nMAssay Description:Beta-1 adrenergic receptor binding affinity in CHO cells expressing cloned human receptor in the presence of 125 I-iodocyanopindololMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed