BDBM50076130 (S)-2-(4-{[(1H-Imidazol-4-ylmethyl)-amino]-methyl}-2-naphthalen-1-yl-benzoylamino)-4-methyl-pentanoic acid::CHEMBL28367

SMILES CC(C)C[C@H](NC(=O)c1ccc(CNCc2cnc[nH]2)cc1-c1cccc2ccccc12)C(O)=O

InChI Key InChIKey=LQNDTMZXYCNVNE-SANMLTNESA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50076130   

LigandPNGBDBM50076130((S)-2-(4-{[(1H-Imidazol-4-ylmethyl)-amino]-methyl}...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vivo for inhibition of farnesylation based on the inhibition of H-Ras processing.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50076130((S)-2-(4-{[(1H-Imidazol-4-ylmethyl)-amino]-methyl}...)
Affinity DataIC50:  1.00E+4nMAssay Description:In vitro inhibition of [3H]-FPP incorporation into H-Ras-CVLS by Farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076130((S)-2-(4-{[(1H-Imidazol-4-ylmethyl)-amino]-methyl}...)
Affinity DataIC50:  44nMAssay Description:In vitro inhibition of [3H]-GGPP incorporation into H-Ras-CVLL by Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed