BDBM50077448 CHEMBL299720::{(R)-2-[4-(4-Dimethylamino-phenoxy)-benzenesulfonyl]-1,2,3,4-tetrahydro-isoquinolin-3-yl}-oxo-acetic acid

SMILES CN(C)c1ccc(Oc2ccc(cc2)S(=O)(=O)N2Cc3ccccc3C[C@@H]2C(=O)C(O)=O)cc1

InChI Key InChIKey=XIMLFZSNGXTRSL-HSZRJFAPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50077448   

TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077448(CHEMBL299720 | {(R)-2-[4-(4-Dimethylamino-phenoxy)...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed