BDBM50078141 CHEMBL3417527
SMILES CNc1ncc(cn1)-c1ccc(cc1)[C@@](C)(C1CC1)c1noc(n1)-c1cnn(CC(=O)N(C)C)c1
InChI Key InChIKey=RSBXBWGJEUGOFA-VWLOTQADSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50078141
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Displacement of [125I]-L-691831 from human FLAP expressed in insect SF9 cell membranes after 2 hrs by Topcount analysisMore data for this Ligand-Target Pair
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of FLAP in calcimycin-stimulated human whole blood assessed as inhibition of LTB4 synthesis preincubated for 15 mins followed by calcimyci...More data for this Ligand-Target Pair