BDBM50078383 CHEMBL3414577

SMILES Cc1cc(sn1)-c1cc(F)c2nnc(n2c1)[C@](C)(F)c1ccc2ncccc2c1

InChI Key InChIKey=FVLLNQSZSCOJJU-OAQYLSRUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50078383   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50078383(CHEMBL3414577)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant c-Met kinase domain (unknown origin) incubated for 30 mins using gastrin peptide substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50078383(CHEMBL3414577)
Affinity DataIC50:  6nMAssay Description:Inhibition of HGF-stimulated c-Met autophosphorylation in serum starved human PC3 cells pre-incubated for 1 hr followed by human recombinant HGF stim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed