BDBM50079751 CHEMBL63426::N*3*-Cyclopropyl-7-(4-isopropyl-benzyl)-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine

SMILES CC(C)c1ccc(Cn2ccc3c2ccc2nc(NC4CC4)nc(N)c32)cc1

InChI Key InChIKey=AVXQPEKZIGPIJW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50079751   

TargetProteinase-activated receptor 1(Homo sapiens (Human))
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50079751(CHEMBL63426 | N*3*-Cyclopropyl-7-(4-isopropyl-benz...)
Affinity DataIC50:  56nMAssay Description:Antagonist activity at PAR1 in human platelet membranes assessed as inhibition of interaction of PAR1 with [Ala-Phe(p-F)-Arg-Cha-HArg-Tyr-NH2] by Chr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50079751(CHEMBL63426 | N*3*-Cyclopropyl-7-(4-isopropyl-benz...)
Affinity DataIC50:  56nMAssay Description:Inhibitory activity against binding to Thrombin receptor 1 (PAR-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed