BDBM50080132 CHEMBL3415976

SMILES CCN(CC)Cc1cccn1-c1ccc(cc1)N1C[C@H](CNC(=O)c2ccc(Cl)s2)OC1=O

InChI Key InChIKey=MECUMEVXEZZBIK-FQEVSTJZSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50080132   

TargetCoagulation factor X(Oryctolagus cuniculus)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50080132(CHEMBL3415976)
Affinity DataIC50:  750nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50080132(CHEMBL3415976)
Affinity DataIC50:  2nMAssay Description:Inhibition of human F10a using S-2765 as substrate after 45 mins by spectra max analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Oryctolagus cuniculus)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50080132(CHEMBL3415976)
Affinity DataIC50:  460nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50080132(CHEMBL3415976)
Affinity DataIC50:  150nMAssay Description:Inhibition of F10a in human plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50080132(CHEMBL3415976)
Affinity DataIC50:  300nMAssay Description:Inhibition of F10a in human plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed