BDBM50082923 6-(9H-Acridin-10-ylmethyl)-pteridine-2,4-diamine::6-(acridin-10(9H)-ylmethyl)pteridine-2,4-diamine::CHEMBL144839

SMILES Nc1nc(N)c2nc(CN3c4ccccc4Cc4ccccc34)cnc2n1

InChI Key InChIKey=VMBSXLVZCRYQJX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50082923   

TargetDihydrofolate reductase(Mycobacterium avium)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50082923(6-(9H-Acridin-10-ylmethyl)-pteridine-2,4-diamine |...)
Affinity DataIC50:  17nMAssay Description:Inhibitory activity of the compound against DHFR (Dihydrofolate reductase) from Mycobacterium aviumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50082923(6-(9H-Acridin-10-ylmethyl)-pteridine-2,4-diamine |...)
Affinity DataIC50:  29nMAssay Description:Inhibitory activity of the compound against DHFR (Dihydrofolate reductase) from Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50082923(6-(9H-Acridin-10-ylmethyl)-pteridine-2,4-diamine |...)
Affinity DataIC50:  42nMAssay Description:Inhibitory activity of the compound against DHFR (Dihydrofolate reductase) from Pneumocystis carinii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50082923(6-(9H-Acridin-10-ylmethyl)-pteridine-2,4-diamine |...)
Affinity DataIC50:  27nMAssay Description:Inhibitory activity of the compound against DHFR (Dihydrofolate reductase) from Rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed