BDBM50083219 4-{3-[4-(2-Benzhydryloxy-ethyl)-piperazin-1-yl]-propyl}-phenol::CHEMBL145942

SMILES Oc1ccc(CCCN2CCN(CCOC(c3ccccc3)c3ccccc3)CC2)cc1

InChI Key InChIKey=RJIJZYPZGVMUQS-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50083219   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083219(4-{3-[4-(2-Benzhydryloxy-ethyl)-piperazin-1-yl]-pr...)
Affinity DataKi:  15nMAssay Description:Binding affinity against dopamine transporter labelled with [125I]- RTI-55 in rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083219(4-{3-[4-(2-Benzhydryloxy-ethyl)-piperazin-1-yl]-pr...)
Affinity DataKi:  894nMAssay Description:Binding affinity against Serotonin transporter (SERT) labelled with [125I]-RTI-55 in rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083219(4-{3-[4-(2-Benzhydryloxy-ethyl)-piperazin-1-yl]-pr...)
Affinity DataIC50:  872nMAssay Description:Reuptake inhibition of [3H]-5-HT (5-HT) in rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083219(4-{3-[4-(2-Benzhydryloxy-ethyl)-piperazin-1-yl]-pr...)
Affinity DataIC50:  17.4nMAssay Description:Reuptake inhibition of [3H]-labeled dopamine (DA) in rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed