BDBM50083950 (S)-(+)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric acid[(S)-(+)-m-nicotinylbenzoylalanine]::(S)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric acid::CHEMBL22740

SMILES N[C@@H](CC(=O)c1cccc(c1)[N+]([O-])=O)C(O)=O

InChI Key InChIKey=KBJZPNMDKSNLIZ-QMMMGPOBSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50083950   

TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50083950((S)-(+)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric a...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of Kynurenine-3-hydroxylase enzyme isolated from the rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50083950((S)-(+)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric a...)
Affinity DataIC50:  500nMAssay Description:Tested for inhibitory activity against kynurenine 3-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50083950((S)-(+)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric a...)
Affinity DataIC50:  900nMAssay Description:Inhibition of KMO in rat brain homogenates using kynurenine as substrate measured after 5 to 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50083950((S)-(+)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric a...)
Affinity DataIC50:  900nMAssay Description:Inhibition of KMO in rat brain homogenates using kynurenine as substrate measured after 5 to 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynureninase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50083950((S)-(+)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric a...)
Affinity DataIC50:  6.00E+4nMAssay Description:Tested for inhibitory activity against kynureninase from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article