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Found 4 Enz. Inhib. hit(s) with Target = 'Kynurenine 3-monooxygenase' and Ligand = 'BDBM50083950'
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50083950((S)-(+)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric a...)
Affinity DataIC50:  500nMAssay Description:Tested for inhibitory activity against kynurenine 3-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50083950((S)-(+)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric a...)
Affinity DataIC50:  900nMAssay Description:Inhibition of KMO in rat brain homogenates using kynurenine as substrate measured after 5 to 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50083950((S)-(+)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric a...)
Affinity DataIC50:  900nMAssay Description:Inhibition of KMO in rat brain homogenates using kynurenine as substrate measured after 5 to 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50083950((S)-(+)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric a...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of Kynurenine-3-hydroxylase enzyme isolated from the rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed