BDBM50084954 CHEMBL443762::Methanesulfonic acid 4-{[2'-methyl-4'-(5-methyl-[1,3,4]oxadiazol-2-yl)-biphenyl-4-carbonyl]-amino}-2-(4-methyl-piperazin-1-yl)-phenyl ester

SMILES CN1CCN(CC1)c1cc(NC(=O)c2ccc(cc2)-c2ccc(cc2C)-c2nnc(C)o2)ccc1OS(C)(=O)=O

InChI Key InChIKey=FRSKIBLQHPOBGH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50084954   

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50084954(CHEMBL443762 | Methanesulfonic acid 4-{[2'-methyl-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition affinity against 5-HT-1D receptor in bovine caudate nucleus using radio binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50084954(CHEMBL443762 | Methanesulfonic acid 4-{[2'-methyl-...)
Affinity DataIC50:  70nMAssay Description:Inhibition affinity against 5-HT-1B receptor in rat frontal cortex using radio binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50084954(CHEMBL443762 | Methanesulfonic acid 4-{[2'-methyl-...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of 5-hydroxytryptamine reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50084954(CHEMBL443762 | Methanesulfonic acid 4-{[2'-methyl-...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition activity against 5-hydroxytryptamine 1A receptor in rat hippocampus membranes using radio binding assaysMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed