BDBM50085288 1-{2-[4-(Biphenyl-4-yloxy)-phenoxy]-ethyl}-pyrrolidine::CHEMBL162432

SMILES C(CN1CCCC1)Oc1ccc(Oc2ccc(cc2)-c2ccccc2)cc1

InChI Key InChIKey=JOAPAHXFXLAMGI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50085288   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50085288(1-{2-[4-(Biphenyl-4-yloxy)-phenoxy]-ethyl}-pyrroli...)
Affinity DataIC50:  6.60nMAssay Description:Inhibitory activity was determined against Leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50085288(1-{2-[4-(Biphenyl-4-yloxy)-phenoxy]-ethyl}-pyrroli...)
Affinity DataIC50:  140nMAssay Description:Inhibitory activity was determined for LTB4 production in human whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed