BDBM50085449 (3S,6S,8S,8aS)-6-Benzyl-6-hydroxy-8-methoxy-5-oxo-octahydro-indolizine-3-carboxylic acid 4-carbamimidoyl-benzylamide; hydrochloride::CHEMBL558594

SMILES CO[C@H]1C[C@@](O)(Cc2ccccc2)C(=O)N2[C@H]1CC[C@H]2C(=O)NCc1ccc(cc1)C(N)=N

InChI Key InChIKey=VQQKGVYMJPVDSD-UKDJSQQHSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50085449   

TargetProthrombin(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50085449((3S,6S,8S,8aS)-6-Benzyl-6-hydroxy-8-methoxy-5-oxo-...)
Affinity DataKi:  125nMAssay Description:Concentration required for 50 percent inhibition of ProthrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50085449((3S,6S,8S,8aS)-6-Benzyl-6-hydroxy-8-methoxy-5-oxo-...)
Affinity DataIC50:  3.50E+4nMAssay Description:Compound was tested for inhibitory activity against Coagulation factor XIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50085449((3S,6S,8S,8aS)-6-Benzyl-6-hydroxy-8-methoxy-5-oxo-...)
Affinity DataIC50:  110nMAssay Description:Compound was tested for inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50085449((3S,6S,8S,8aS)-6-Benzyl-6-hydroxy-8-methoxy-5-oxo-...)
Affinity DataIC50:  7.10E+4nMAssay Description:Compound was tested for inhibitory activity against PlasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50085449((3S,6S,8S,8aS)-6-Benzyl-6-hydroxy-8-methoxy-5-oxo-...)
Affinity DataIC50:  251nMAssay Description:Concentration required for 50 percent inhibition of ProthrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50085449((3S,6S,8S,8aS)-6-Benzyl-6-hydroxy-8-methoxy-5-oxo-...)
Affinity DataIC50:  520nMAssay Description:Compound was tested for inhibitory activity against Coagulation factor VIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed