BDBM50085476 1-(3,4-Dimethoxy-phenyl)-3-(3-ethyl-pentanoyl)-4-hydroxy-6,7,8-trimethoxy-naphthalene-2-carboxylic acid methyl ester::CHEMBL18380::S-8921

SMILES CCC(CC)CC(=O)c1c(O)c2cc(OC)c(OC)c(OC)c2c(-c2ccc(OC)c(OC)c2)c1C(=O)OC

InChI Key InChIKey=QEJQEIIPZKQCNP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50085476   

TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50085476(1-(3,4-Dimethoxy-phenyl)-3-(3-ethyl-pentanoyl)-4-h...)
Affinity DataIC50: >1.85E+5nMAssay Description:In vitro Inhibition of apical sodium-dependent bile acid transporter by measuring the uptake of [3H]-taurocholate in hamster ileal ringMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50085476(1-(3,4-Dimethoxy-phenyl)-3-(3-ethyl-pentanoyl)-4-h...)
Affinity DataIC50:  2.55E+3nMAssay Description:In vitro for inhibition of [14C]-taurocholate uptake in baby hamster kidney cells transfected with the cDNA of human Bile acid transporter (H14 cells...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed