BDBM50086339 4-(4-Ethynyl-phenyl)-1-methyl-piperidine-3-carboxylic acid methyl ester::CHEMBL279480

SMILES COC(=O)C1CN(C)CC[C@@H]1c1ccc(cc1)C#C

InChI Key InChIKey=WDZZOOWETOTPBN-GICMACPYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50086339   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50086339(4-(4-Ethynyl-phenyl)-1-methyl-piperidine-3-carboxy...)
Affinity DataKi:  175nMAssay Description:Inhibition of [3H]5-HT uptake by Serotonin transporter of rat midbrain or parietal synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50086339(4-(4-Ethynyl-phenyl)-1-methyl-piperidine-3-carboxy...)
Affinity DataKi:  187nMAssay Description:Inhibition of [3H]DA uptake by dopamine transporter of rat striata synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50086339(4-(4-Ethynyl-phenyl)-1-methyl-piperidine-3-carboxy...)
Affinity DataKi:  364nMAssay Description:Inhibition of [3H]NE uptake by Norepinephrine transporter of rat occipital cortex synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed