BDBM50086449 CHEMBL3426224::US10266537, Compound 8

SMILES CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc3nn(C)c4ncnc(N)c34)cc2C(F)(F)F)CC1

InChI Key InChIKey=JPOSZHLAYKQNKX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50086449   

TargetProto-oncogene tyrosine-protein kinase Src [1-530](Homo sapiens (Human))
St. Chuan University

US Patent
LigandPNGBDBM50086449(CHEMBL3426224 | US10266537, Compound 8)
Affinity DataIC50:  7nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50086449(CHEMBL3426224 | US10266537, Compound 8)
Affinity DataIC50:  7nMAssay Description:Inhibition of human SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed