BDBM50087826 CHEMBL3426789

SMILES Cc1ccccc1COc1ccc(cc1)C1C2=C(CC(C)(C)CC2=O)OC2=C1C(=O)CC(C)(C)C2

InChI Key InChIKey=UEKIYVKPQNKSDI-UHFFFAOYSA-N

Data  3 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50087826   

TargetDelta-type opioid receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50087826(CHEMBL3426789)
Affinity DataKi:  3nMAssay Description:Positive allosteric modulation of human delta opioid receptor expressed in CHO cell membranes assessed as TAN67 Ki at 10 uM after 90 mins by [3H]-dip...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50087826(CHEMBL3426789)
Affinity DataKi:  5nMAssay Description:Positive allosteric modulation of human delta opioid receptor expressed in CHO cell membranes assessed as SNC80 Ki at 10 uM after 90 mins by [3H]-dip...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50087826(CHEMBL3426789)
Affinity DataKi:  7nMAssay Description:Positive allosteric modulation of human delta opioid receptor expressed in CHO cell membranes assessed as leu-enkephalin Ki at 10 uM after 90 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50087826(CHEMBL3426789)
Affinity DataEC50:  2.34E+8nMAssay Description:Inhibition of human DOR expressed in CHO cells assessed as reduction in Leu-enkephalin induced cAMP level by measuring Leu-enkephalin pEC50 measured ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50087826(CHEMBL3426789)
Affinity DataEC50:  2.60E+3nMAssay Description:Positive allosteric modulation of human mu opioid receptor-1 expressed in CHO cells assessed as potentiation of endomorphin 1-induced response after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50087826(CHEMBL3426789)
Affinity DataEC50:  3.47E+7nMAssay Description:Inhibition of human DOR expressed in CHO cells assessed as reduction in Leu-enkephalin induced ERK1/2 phosphorylation level by measuring Leu-enkephal...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50087826(CHEMBL3426789)
Affinity DataEC50:  30nMAssay Description:Positive allosteric modulation of human delta opioid receptor-1 expressed in CHO cells assessed as potentiation of leu-enkephalin-induced response af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed