BDBM50088420 3-Hydroxymethyl-5-[6-(3-iodo-benzylamino)-purin-9-yl]-cyclopentane-1,2-diol::CHEMBL71385

SMILES OC[C@H]1C[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCc3cccc(I)c3)ncnc12

InChI Key InChIKey=JIBVHQBGLJITFH-CUBALJKWSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50088420   

TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50088420(3-Hydroxymethyl-5-[6-(3-iodo-benzylamino)-purin-9-...)
Affinity DataKi:  1.96E+3nMAssay Description:Displacement of [125I]- AB-MECA from human adenosine A3 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50088420(3-Hydroxymethyl-5-[6-(3-iodo-benzylamino)-purin-9-...)
Affinity DataKi:  2.59E+4nMAssay Description:Displacement of [3H]R-PIA from rat brain membrane Adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50088420(3-Hydroxymethyl-5-[6-(3-iodo-benzylamino)-purin-9-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Stimulation of [35S]GTP-gamma-S, against human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50088420(3-Hydroxymethyl-5-[6-(3-iodo-benzylamino)-purin-9-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding to human adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed