BDBM50090621 4-(4-Methanesulfonyl-phenyl)-3-(4-methoxy-phenyl)-1-phenyl-1,5-dihydro-pyrrol-2-one::CHEMBL300021

SMILES COc1ccc(cc1)C1=C(CN(C1=O)c1ccccc1)c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=FJBKKMJBVLOMRG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50090621   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50090621(4-(4-Methanesulfonyl-phenyl)-3-(4-methoxy-phenyl)-...)
Affinity DataIC50:  340nMAssay Description:Biochemical index for Prostaglandin G/H synthase 2 measured as, PGE-2 levels in lipopolysaccharide (LPS)-challenged human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50090621(4-(4-Methanesulfonyl-phenyl)-3-(4-methoxy-phenyl)-...)
Affinity DataIC50:  2.68E+3nMAssay Description:Biochemical index for Prostaglandin G/H synthase 1 measured as, tromboxane 2 (TXB2) levels following blood coagulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed