BDBM50090628 3-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-1-(4-trifluoromethyl-phenyl)-1,5-dihydro-pyrrol-2-one::CHEMBL49011

SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)N(C1)c1ccc(cc1)C(F)(F)F)c1ccc(F)cc1

InChI Key InChIKey=TVBSMSWWIVWXMI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50090628   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50090628(3-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-1...)
Affinity DataIC50:  950nMAssay Description:Biochemical index for Prostaglandin G/H synthase 2 measured as, PGE-2 levels in lipopolysaccharide (LPS)-challenged human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM50090628(3-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-1...)
Affinity DataIC50:  7.20E+3nMAssay Description:Biochemical index for Prostaglandin G/H synthase 1 measured as, tromboxane 2 (TXB2) levels following blood coagulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed