BDBM50091167 4-[2-(5-Bromo-pyridin-3-yl)-4-trifluoromethyl-imidazol-1-yl]-benzenesulfonamide::CHEMBL106023

SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(nc1-c1cncc(Br)c1)C(F)(F)F

InChI Key InChIKey=GAJUPZYRMFPEFR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50091167   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091167(4-[2-(5-Bromo-pyridin-3-yl)-4-trifluoromethyl-imid...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
University Of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50091167(4-[2-(5-Bromo-pyridin-3-yl)-4-trifluoromethyl-imid...)
Affinity DataIC50:  3.38E+8nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50091167(4-[2-(5-Bromo-pyridin-3-yl)-4-trifluoromethyl-imid...)
Affinity DataIC50:  339nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50091167(4-[2-(5-Bromo-pyridin-3-yl)-4-trifluoromethyl-imid...)
Affinity DataIC50:  340nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed