BDBM50091208 5-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazol-2-yl]-2-methyl-pyridine::CHEMBL325790

SMILES Cc1ccc(cn1)-c1nc(cn1-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F

InChI Key InChIKey=TZUKXDRCVJCLLL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50091208   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091208(5-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
University Of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50091208(5-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50:  5.49E+8nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50091208(5-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50:  1.82E+3nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50091208(5-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed