BDBM50091276 CHEMBL3582190
SMILES CC(=O)Nc1cccc(c1)-c1cnc2[nH]c3cnc(cc3c2c1)C#N
InChI Key InChIKey=QBZYUGXSSSASTB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50091276
Affinity DataEC50: 425nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as phosphorylation of histone H3 after 24 hrs by checkpoint abrogation cellular assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant Chk1 using biotinylated AKT substrate after 30 mins by Alphascreen biochemical assayMore data for this Ligand-Target Pair