BDBM50092930 3-[3-Chloro-4-(2,4-dichloro-phenylsulfanyl)-phenyl]-1-(4-methyl-piperazin-1-yl)-propenone::CHEMBL319484

SMILES CN1CCN(CC1)C(=O)\C=C\c1ccc(Sc2ccc(Cl)cc2Cl)c(Cl)c1

InChI Key InChIKey=OPVNCZMKIWFYNT-XVNBXDOJSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50092930   

TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50092930(3-[3-Chloro-4-(2,4-dichloro-phenylsulfanyl)-phenyl...)
Affinity DataIC50:  1.10E+3nMAssay Description:Ability to antagonise the Leukocyte function-associated Antigen-1/ Intracellular Adhesion molecule-1 interaction (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50092930(3-[3-Chloro-4-(2,4-dichloro-phenylsulfanyl)-phenyl...)
Affinity DataIC50:  1.10E+3nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed