BDBM50092941 3-[3-Chloro-4-(2,4-dichloro-phenylsulfanyl)-phenyl]-1-morpholin-4-yl-propenone::CHEMBL421582

SMILES Clc1ccc(Sc2ccc(\C=C\C(=O)N3CCOCC3)cc2Cl)c(Cl)c1

InChI Key InChIKey=FAEVSCKIBUDMQJ-QHHAFSJGSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50092941   

TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50092941(3-[3-Chloro-4-(2,4-dichloro-phenylsulfanyl)-phenyl...)
Affinity DataIC50:  460nMAssay Description:Ability to antagonise the Leukocyte function-associated Antigen-1/ Intracellular Adhesion molecule-1 interaction (LFA-1/ICAM-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50092941(3-[3-Chloro-4-(2,4-dichloro-phenylsulfanyl)-phenyl...)
Affinity DataIC50:  460nMAssay Description:Ability to block the interaction between integrin LFA-1 and its adhesion partner ICAM-1 in a time-resolved fluorescent LFA-1/ICAM-1 biochemical inter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed