BDBM50095562 1-(4-Butoxy-benzenesulfonyl)-4-(1,1-dioxo-1lambda*6*-thiomorpholin-4-yl)-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL144176
SMILES CCCCOc1ccc(cc1)S(=O)(=O)N1C[C@H](C[C@@H]1C(=O)NO)N1CCS(=O)(=O)CC1
InChI Key InChIKey=HPIJZAVGIHKGTA-MAUKXSAKSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50095562
Affinity DataIC50: 0.900nMAssay Description:Inhibition of matrix metalloproteinase-13 (collagenase-3)More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-7 (matrilysin, MMP-7)More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase -1 (collagenase-1)More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase -3 (stromelysin)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase -2 (gelatinase-A)More data for this Ligand-Target Pair