BDBM50095586 4-(1,1-Dioxo-1lambda*6*-thiomorpholin-4-yl)-1-(4-methoxy-benzenesulfonyl)-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL356079

SMILES COc1ccc(cc1)S(=O)(=O)N1C[C@H](C[C@@H]1C(=O)NO)N1CCS(=O)(=O)CC1

InChI Key InChIKey=HZELUBQHAZKZKC-SWLSCSKDSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50095586   

TargetStromelysin-1(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095586(4-(1,1-Dioxo-1lambda*6*-thiomorpholin-4-yl)-1-(4-m...)
Affinity DataIC50:  23nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase -3 (stromelysin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095586(4-(1,1-Dioxo-1lambda*6*-thiomorpholin-4-yl)-1-(4-m...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibitory activity against human recombinant matrix metalloproteinase-13 (collagenase-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095586(4-(1,1-Dioxo-1lambda*6*-thiomorpholin-4-yl)-1-(4-m...)
Affinity DataIC50:  7.10E+3nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-7 (matrilysin, MMP-7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095586(4-(1,1-Dioxo-1lambda*6*-thiomorpholin-4-yl)-1-(4-m...)
Affinity DataIC50:  300nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase -1 (collagenase-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed