BDBM50095592 4-Methanesulfonylamino-1-[4-(pyridin-4-yloxy)-benzenesulfonyl]-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL148178

SMILES CS(=O)(=O)N[C@H]1C[C@@H](N(C1)S(=O)(=O)c1ccc(Oc2ccncc2)cc1)C(=O)NO

InChI Key InChIKey=DZVJLUYVLJYLGY-BLLLJJGKSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50095592   

TargetMatrilysin(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095592(4-Methanesulfonylamino-1-[4-(pyridin-4-yloxy)-benz...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-7 (matrilysin, MMP-7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095592(4-Methanesulfonylamino-1-[4-(pyridin-4-yloxy)-benz...)
Affinity DataIC50:  450nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase -1 (collagenase-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095592(4-Methanesulfonylamino-1-[4-(pyridin-4-yloxy)-benz...)
Affinity DataIC50:  0.800nMAssay Description:In vitro inhibitory activity against human recombinant matrix metalloproteinase-13 (collagenase-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095592(4-Methanesulfonylamino-1-[4-(pyridin-4-yloxy)-benz...)
Affinity DataIC50:  22nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase -3 (stromelysin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed