BDBM50096149 CHEMBL3593993

SMILES NC(=O)c1cc(F)cc2[nH]c(nc12)-c1ccc(cc1F)-c1ccc(NC(=O)C2CC2)cc1F

InChI Key InChIKey=WBYLPCYRGKFIOB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50096149   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Malaya

Curated by ChEMBL
LigandPNGBDBM50096149(CHEMBL3593993)
Affinity DataIC50:  4.80E+4nMAssay Description:Inhibition of DHODH (unknown origin) using L-DHO, DUQ, DCIP as substrate preincubated for 30 mins followed by substrate addition measured after 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University Of Malaya

Curated by ChEMBL
LigandPNGBDBM50096149(CHEMBL3593993)
Affinity DataIC50:  84nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as incorporation of biotinylated poly (ADP-ribose) onto histone protein after 60 mins by TACS-Sapphire...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed