BDBM50098005 CHEMBL354677::N-Isopropyl-2-(1-methyl-2-o-tolyl-1H-indol-3-yl)-N-pyridin-4-ylmethyl-acetamide

SMILES CC(C)N(Cc1ccncc1)C(=O)Cc1c(-c2ccccc2C)n(C)c2ccccc12

InChI Key InChIKey=QBIOEIXFXALQMC-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50098005   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50098005(CHEMBL354677 | N-Isopropyl-2-(1-methyl-2-o-tolyl-1...)
Affinity DataEC50:  1.06E+3nMAssay Description:Inhibition of HDJ-2 farnesylation in PSN-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50098005(CHEMBL354677 | N-Isopropyl-2-(1-methyl-2-o-tolyl-1...)
Affinity DataIC50:  12nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed