BDBM50098016 CHEMBL171214::N-Cyclopropyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-4-ylmethyl-acetamide

SMILES O=C(Cc1c([nH]c2ccccc12)-c1ccccc1)N(Cc1ccncc1)C1CC1

InChI Key InChIKey=RMWSUCRYTTWVOL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098016   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50098016(CHEMBL171214 | N-Cyclopropyl-2-(2-phenyl-1H-indol-...)
Affinity DataIC50:  171nMAssay Description:Inhibition of FPP incorporation into biotinylated K-Ras-derived peptide by human farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed